TRILURON^® may provide up to 6 months of relief from osteoarthritis (OA) knee pain with just 3 injections¹

TRILURON^® may be an effective pain-relief option if you have knee osteoarthritis. TRILURON^® was shown to provide long-lasting relief from OA knee pain in a clinical study in which patients were given 3 injections of TRILURON^® once per week for 3 weeks.¹ Patients reported an average reduction in pain of 38% after 6 months of treatment.

What is TRILURON^®?

TRILURON^® is a viscous solution containing hyaluronate injected directly into your knee that acts like a lubricant and shock absorber. Hyaluronan is a natural substance found in high amounts in your body’s joint tissue and joint fluid.

Frequently asked questions about TRILURON^®²

How is TRILURON^® given?

Your doctor will inject TRILURON^® into your knee.

How many injections will I receive?

TRILURON^® will be administered in a convenient 3-injection regimen, with each injection given 1 week apart.

How soon will I feel pain relief?

Your response to TRILURON^® may vary, depending on the severity of your OA, degree of pain, and pre-existing medical conditions.

How long will pain relief last?

Three injections given at weekly intervals can provide most patients with long-lasting pain relief for up to 6 months. The duration of pain relief you experience may vary.

Can I repeat my treatment?

TRILURON^® therapy can be safely repeated if your doctor feels it is appropriate. Please consult with your doctor to find out whether you can benefit from repeat treatment.

Can I take other medications?

TRILURON^® has no known drug interactions. However, you should consult with your doctor before taking any other medications while being treated with TRILURON^®.

What about side effects?

Local side effects sometimes seen with TRILURON^® include joint swelling/pain, injection site pain, local skin reactions (rash, ecchymosis) and injection site warmth. Usually, these disappear within a few days of resting and/or applying ice.

Are there any reasons why I should not take TRILURON^®?

You should not take this product if you have had any previous allergic reaction to TRILURON^® or similar material, e.g., hyaluronate products. You should not have an injection into the knee if you have infections or skin diseases around the injection site.

Indication

TRILURON^® is used to relieve knee pain caused by osteoarthritis. It is used for patients who do not get adequate pain relief from simple pain relievers or from exercise and physical therapy.

Important Safety Information

Before receiving TRILURON^®, tell your doctor if you are allergic to hyaluronan products or have an infection or skin disease in the area of the injection site. Tell your doctor if you think you are pregnant or if you are nursing a child or if you are allergic to bird proteins, feathers or egg products. TRILURON^® is not approved for relieving pain in other joints besides the knee or for injection with other substances in your knee joint. TRILURON^® has not been tested in pregnant or nursing women or children. The effectiveness of repeat treatment cycles has not been established. Injections must only be given by trained and licensed healthcare professionals. Talk to your doctor before resuming strenuous or prolonged weight-bearing activities after treatment.

The side effects most commonly seen after injection into the knee joint are knee pain, discomfort, swelling, fluid in the joint, warmth or redness at the injection site. These symptoms usually disappear within a few days by resting the injected knee and applying ice. Sometimes these side effects may be more severe and last longer. Signs of an allergic reaction many include rash, itching hives, flushing, swelling of your face, tongue or throat, difficulty breathing or swallowing and shortness of breath. If any of these symptoms or signs appear after you are injected, or if you have any other problems, contact your doctor. Please see package insert for full warnings, precautions, and possible side effects.

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Please see Full Patient Labeling.

TRILURON® may provide up to 6 months of relief from osteoarthritis (OA) knee pain with just 3 injections1

What is TRILURON®?

Frequently asked questions about TRILURON®2

References

TRILURON^® may provide up to 6 months of relief from osteoarthritis (OA) knee pain with just 3 injections¹

What is TRILURON^®?

Frequently asked questions about TRILURON^®²